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Wogonoside

Cat. No.:YN280128

  • CAS No. :51059-44-0

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    • 参考文献
    • 产品名称: Wogonoside
      CAS No.: 51059-44-0
      Chemical Name: 5-hydroxy-8-methoxy-4-oxo-2-phenyl-4H-1-benzopyran-7-yl β-D-glucopyranosiduronic acid
      Synonyms:汉黄芩苷,Glychionide B,Oroxindin,Wogonin 7-O-glucuronide
      分子量:460.39
      分子式:C₂₂H₂₀O₁₁
      SMILES:O=C(C=C(C1=CC=CC=C1)O2)C3=C2C(OC)=C(O[C@@H]4O[C@H](C(O)=O)[C@@H](O)[C@H](O)[C@H]4O)C=C3O
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: Wogonoside 是从黄芩中分离得到的一种黄酮类苷化合物,具有抗炎作用。Wogonoside 通过调节 MAPK-mTOR 通路诱导乳腺癌细胞的自噬。
      IC50和靶点:
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    • Sun, Y., Zhao, Y., Yao, J., et al.Wogonoside protects against dextran sulfate sodium-induced experimental colitis in mice by inhibiting NF-κB and NLRP3 inflammasome activationBiochem. Pharmacol.94(2),142-154(2015)

      Sun, Y., Zou, H., Hu, C., et al.Wogonoside induces autophagy in MDA-MB-231 cells by regulating MAPK-mTOR pathwayFood. Chem. Toxicol.51,53-60(2013)

      Huang, Y., Zhao, K., Hu, Y., et al.Wogonoside inhibits angiogenesis in breast cancer via suppressing Wnt/β-catenin pathwayMol. Carcinog.55(11),1598-1612(2016)

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