Wogonoside
Cat. No.:YN280128
CAS No. :51059-44-0
产品名称: | Wogonoside |
CAS No.: | 51059-44-0 |
Chemical Name: | 5-hydroxy-8-methoxy-4-oxo-2-phenyl-4H-1-benzopyran-7-yl β-D-glucopyranosiduronic acid |
Synonyms: | 汉黄芩苷,Glychionide B,Oroxindin,Wogonin 7-O-glucuronide |
分子量: | 460.39 |
分子式: | C₂₂H₂₀O₁₁ |
SMILES: | O=C(C=C(C1=CC=CC=C1)O2)C3=C2C(OC)=C(O[C@@H]4O[C@H](C(O)=O)[C@@H](O)[C@H](O)[C@H]4O)C=C3O |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Wogonoside 是从黄芩中分离得到的一种黄酮类苷化合物,具有抗炎作用。Wogonoside 通过调节 MAPK-mTOR 通路诱导乳腺癌细胞的自噬。 |
IC50和靶点: | |
In Vitro: | |
In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: |
Sun, Y., Zhao, Y., Yao, J., et al.Wogonoside protects against dextran sulfate sodium-induced experimental colitis in mice by inhibiting NF-κB and NLRP3 inflammasome activationBiochem. Pharmacol.94(2),142-154(2015)
Sun, Y., Zou, H., Hu, C., et al.Wogonoside induces autophagy in MDA-MB-231 cells by regulating MAPK-mTOR pathwayFood. Chem. Toxicol.51,53-60(2013)
Huang, Y., Zhao, K., Hu, Y., et al.Wogonoside inhibits angiogenesis in breast cancer via suppressing Wnt/β-catenin pathwayMol. Carcinog.55(11),1598-1612(2016)