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Schisandrin

Cat. No.:YN280133

  • CAS No. :7432-28-2

    • 产品资料
    • 生物活性
    • 参考文献
    • 产品名称: Schisandrin
      CAS No.: 7432-28-2
      Chemical Name: (6S,7S,12aR)-5,6,7,8-tetrahydro-1,2,3,10,11,12-hexamethoxy-6,7-dimethyl-dibenzo[a,c]cycloocten-6-ol
      Synonyms:五味子醇甲; Schizandrol; Schizandrol-A; Wuweizi alcohol-A; Wuweizichun-A
      分子量:432.51
      分子式:C₂₄H₃₂O₇
      SMILES:O[C@]1(C)[C@@H](C)CC2=CC(OC)=C(OC)C(OC)=C2C3=C(OC)C(OC)=C(OC)C=C3C1
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: 五味子醇甲(Schisandrin)是具有抗癌和抗炎症等生物活性的天然化合物。
      IC50和靶点:
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      In Vivo:
      Clinical Trial:
      Solvent & Solubility:
    • Kim, S.-J., Min, H.-Y., Lee, E.J., et al.Growth inhibition and cell cycle arrest in the G0/G1 by schizandrin, a dibenzocyclooctadiene lignan isolated from Schisandra chinensis, on T47D human breast cancer cellsPhytother. Res.24(2),193-197(2010)

      Cheng, H.-Y., Hsieh, M.-T., Wu, C.-R., et al.Schizandrin protects primary cultures of rat cortical cells from glutamate-induced excitotoxicityJ. Pharmacol. Sci.107(1),21-31(2008)

      Bunel, V., Antoine, M.-H., Nortier, J., et al.Protective effects of schizandrin and schizandrin B towards cisplatin nephrotoxicity in vitroJ. Appl. Toxicol.34(12),1311-1319(2013)

      Egashira, N., Kurauchi, K., Iwasaki, K., et al.Schizandrin reverses memory impairment in ratsPhytother. Res.22(1),49-52(2008)

      Han, N.-R., Moon, P.-D., Kim, N.-R., et al.Schisandra chinensis and its main constituent schizandrin attenuate allergic reactions by down-regulating caspase-1 in ovalbumin-sensitized miceAm. J. Chin. Med.45(1),159-172(2017)

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