Schisandrol B
Cat. No.:YN280134
CAS No. :58546-54-6
产品名称: | Schisandrol B |
CAS No.: | 58546-54-6 |
Chemical Name: | (6S,7S,13aR)-5,6,7,8-tetrahydro-1,2,3,13-tetramethoxy-6,7-dimethyl-benzo[3,4]cycloocta[1,2-f][1,3]benzodioxol-6-ol |
Synonyms: | 五味子醇乙; Gomisin-A; TJN-101; Wuweizi alcohol-B |
分子量: | 416.46 |
分子式: | C₂₃H₂₈O₇ |
SMILES: | O[C@@]([C@@H](C)C1)(C)CC2=CC(OC)=C(OC)C(OC)=C2C3=C1C=C4OCOC4=C3OC |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Schisandrol B (Gomisin-A;TJN-101;Wuweizi alcohol-B) 是肝保护传统中药华中五味子的主要活性成分。 |
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Taqguchi, H., and Ikeya, Y.The constituents of Schizandra chinensis BAILL. I. The structures of gomisin A, B and CChem. Pharm. Bull.23(12),3296-3298(1975)
Zeng, H., Jiang, Y., Chen, P., et al.Schisandrol B protects against cholestatic liver injury through pregnane X receptorsBr. J. Pharmacol.174(8),672-688(2017)
Li, X., Sun, J., Fan, X., et al.Schisandrol B promotes liver regeneration after partial hepatectomy in miceEur. J. Pharmacol.818,96-102(2018)
Jiang, Y.-m., Wang, Y., Tan, H.-s., et al.Schisandrol B protects against acetaminopheninduced acute hepatotoxicity in mice via activation of the NRF2/ARE signaling pathwayActa Pharmacol. Sin.37(3),382-389(2016)