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Diosgenin glucoside

Cat. No.:YN280136

  • CAS No. :14144-06-0

    • 产品资料
    • 生物活性
    • 参考文献
    • 产品名称: Diosgenin glucoside
      CAS No.: 14144-06-0
      Chemical Name: (3β,25R)-spirost-5-en-3-yl β-D-glucopyranoside
      Synonyms:延龄草苷
      分子量:576.76
      分子式:C₃₃H₅₂O₈
      SMILES:C[C@@]12[C@]([C@@H]3C)([H])[C@](O[C@]34CC[C@@H](C)CO4)([H])C[C@@]1([H])[C@@](CC=C5[C@@]6(CC[C@H](O[C@]([C@@H]([C@@H](O)[C@@H]7O)O)([H])O[C@@H]7CO)C5)C)([H])[C@]6([H])CC2
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: Diosgenin glucoside 是一种来自Tritulus terrestrisL. 的皂苷元化合物,通过调节小胶质细胞 M1 极化提供神经保护。Diosgenin glucoside 通过调节自噬和减轻细胞凋亡来保护脊髓免受损伤。
      IC50和靶点:
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    • Xu, M., Dong, P., Tian, X., et al.Drug interaction study of natural steroids from herbs specifically toward human UDP-glucuronosyltransferase (UGT) 1A4 and their quantitative structure activity relationship (QSAR) analysis for predictionPharmacol. Res.110,139-150(2016)

      Liu, M.-J., Wang, Z., Ju, Y., et al.The mitotic-arresting and apoptosis-inducing effects of diosgenyl saponins on human leukemia cell linesBiol. Pharm. Bull.27(7),1059-1065(2004)

      Chen, X.-B., Wang, Z.-L., Yang, Q.-Y., et al.Diosgenin glucoside protects against spinal cord injury by regulating autophagy and alleviating apoptosisInt. J. Mol. Sci.19(8),2274(2018)

      Wu, Y., Ye, F., Lu, Y., et al.Diosgenin glucoside protects against myocardial injury in diabetic mice by inhibiting RIP140 signalingAm. J. Transl. Res.10(11),3742-3749(2018)

      Chen, T., Jiang, W., Zhang, H., et al.Protective effect of trillin against ethanol-induced acute gastric lesions in an animal modelRSC Adv.6,20081-20088(2016)

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