Leonurine
Cat. No.:YN280137
CAS No. :24697-74-3
产品名称: | Leonurine |
CAS No.: | 24697-74-3 |
Chemical Name: | 4-hydroxy-3,5-dimethoxy-benzoic acid, 4-[(aminoiminomethyl)amino]butyl ester |
Synonyms: | 益母草碱; SCM-198 |
分子量: | 311.33 |
分子式: | C₁₄H₂₁N₃O₅ |
SMILES: | O=C(OCCCCNC(N)=N)C1=CC(OC)=C(O)C(OC)=C1 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Leonurine 是从Herba leonuri中分离到的生物碱,具有抗氧化、抗炎活性。 |
IC50和靶点: | |
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Zhu, Y.Z., Wu, W., Zhu, Q., et al.Discovery of Leonuri and therapeutical applications: From bench to bedsidePharmacol. Ther.188,26-35(2018)
Xu, L., Jiang, X., Wei, F., et al.Leonurine protects cardiac function following acute myocardial infarction through anti‑apoptosis by the PI3K/AKT/GSK3β signaling pathwayMol. Med. Rep.18(2),1582-1590(2018)
Zhang, L., Li, H.-X., Pan, W.-S., et al.Novel hepatoprotective role of Leonurine hydrochloride against experimental non-alcoholic steatohepatitis mediated via AMPK/SREBP1 signaling pathwayBiomed. Pharmacother.110,571-581(2019)
Yang, L., Liu, G., Zhu, X., et al.The anti-inflammatory and antioxidant effects of leonurine hydrochloride after lipopolysaccharide challenge in broiler chicksPoult. Sci.98(4),1648-1657(2019)