JPH203 dihydrochloride
Cat. No.：YN280159
CAS No. ：1597402-27-1
| 产品名称: | JPH203 dihydrochloride |
| CAS No.: | 1597402-27-1 |
| Chemical Name: | O-[(5-amino-2-phenyl-7-benzoxazolyl)methyl]-3,5-dichloro-L-tyrosine, dihydrochloride |
| Synonyms: | KYT-0353 dihydrochloride |
| 分子量: | 545.24 |
| 分子式: | C₂₃H₂₁Cl₄N₃O₄ |
| SMILES: | N[C@@H](CC1=CC(Cl)=C(C(Cl)=C1)OCC2=C(OC(C3=CC=CC=C3)=N4)C4=CC(N)=C2)C(O)=O.[H]Cl.[H]Cl |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | JPH203 dihydrochloride (KYT-0353 dihydrochloride) 是酪氨酸类似物，为 L 型氨基酸转运载体 (LAT1) 抑制剂，可用于癌症研究。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Oda, K., Hosoda, N., Endo, H., et al.L-type amino acid transporter 1 inhibitors inhibit tumor cell growthCancer Sci.101(1),173-179(2010)
Yun, D.-W., Lee, S.A., Park, M.-G., et al.JPH203, an L-type amino acid transporter 1–selective compound, induces apoptosis of YD-38 human oral cancer cellsJ. Pharmacol. Sci.124(2),208-217(2014)
