Sulfosuccinimidyl oleate sodium
Cat. No.：YN280165
CAS No. ：1212012-37-7
| 产品名称: | Sulfosuccinimidyl oleate sodium |
| CAS No.: | 1212012-37-7 |
| Chemical Name: | 9-octadecenoic acid, 2,5-dioxo-3-sulfo-1-pyrrolidinyl ester, monosodium salt |
| Synonyms: | Sulfo-N-succinimidyl oleate sodium |
| 分子量: | 482.6 |
| 分子式: | C22H36NO7S • Na |
| SMILES: | CCCCCCCC/C=C\CCCCCCCC(ON1C(C(S(O)(=O)=O)CC1=O)=O)=O.[Na+] |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Sulfosuccinimidyl oleate sodium (Sulfo-N-succinimidyl oleate sodium) 是一种长链脂肪酸，抑制脂肪酸向细胞转运。Sulfosuccinimidyl oleate sodium 是一种有效且不可逆的线粒体呼吸链抑制剂。Sulfosuccinimidyl oleate sodium 结合小胶质细胞表面上的CD36受体。具有抗炎作用。 |
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Harmon, C.M., Luce, P., Beth, A.H., et al.Labeling of adipocyte membranes by sulfo-N-succinimidyl derivatives of long-chain fatty acids: Inhibition of fatty acid transportJ. Membr. Biol.121(3),261-268(1991)
Abumrad, N.A., el-Maghrabi, M.R., Amri, E.Z., et al.Cloning of a rat adipocyte membrane protein implicated in binding or transport of long-chain fatty acids that is induced during preadipocyte differentiation. Homology with human CD36J. Biol. Chem.268(24),17665-17668(1993)
Noushmehr, H., D'Amico, E., Farilla, L., et al.Fatty acid translocase (FAT/CD36) is localized on insulin-containing granules in human pancreatic β-cells and mediates fatty acid effects on insulin secretionDiabetes54(2),472-481(2005)
Nicholls, H.T., Kowalski, G., Kennedy, D.J., et al.Hematopoietic cell-restricted deletion of CD36 reduces high-fat diet-induced macrophage infiltration and improves insulin signaling in adipose tissueDiabetes60(4),1100-1110(2011)
