MRT67307 dihydrochloride
Cat. No.：YN280192
| 产品名称: | MRT67307 dihydrochloride |
| CAS No.: | 1781882-89-0 |
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| 分子量: | 464.6 (free-base) |
| 分子式: | C26H36N6O2· xHCl |
| SMILES: | C1CC(C1)C(=O)NCCCNC2=NC(=NC=C2C3CC3)NC4=CC=CC(=C4)CN5CCOCC5 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | MRT67307 dihydrochloride 是IKKε和TBK-1的双抑制剂，IC50分别为 160 和 19 nM。MRT67307 dihydrochloride 也可抑制ULK1和ULK2，IC50分别为 45 和 38 nM。MRT67307 dihydrochloride 还抑制细胞自噬 (autophagy)。 |
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