CCT128930 hydrochloride
Cat. No.：YN280196
CAS No. ：2453324-32-6
| 产品名称: | CCT128930 hydrochloride |
| CAS No.: | 2453324-32-6 |
| Chemical Name: | |
| Synonyms: | |
| 分子量: | 378.3 |
| 分子式: | C18H21Cl2N5 |
| SMILES: | 暂无 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | CCT128930 hydrochloride是一种有效且选择性的AKT抑制剂 (IC50=6 nM)。CCT128930 hydrochloride 通过靶向AKT的 Met282 (PKA-AKT 嵌合体的 Met173)，对PKA激酶 (IC50=168 nM) 具有 28 倍的选择性，对p70S6K(IC50=120 nM) 具有 20 倍的选择性。具有抗肿瘤活性。 |
| IC50和靶点: | [{name:"Akt2:6 nM (IC50)"},{name: "PKA:168 nM (IC50)"},{name: "p70S6K:120 nM (IC50)'}, 'Autophagy', 'Apoptosis'] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
