Zamicastat
Cat. No.：YN360162
CAS No. ：1080028-80-3
| 产品名称: | Zamicastat |
| CAS No.: | 1080028-80-3 |
| Chemical Name: | |
| Synonyms: | BIA 5-1058 |
| 分子量: | 401.47 |
| 分子式: | C₂₁H₂₁F₂N₃OS |
| SMILES: | S=C1N([C@@H]2CC3=CC(F)=CC(F)=C3OC2)C(CCNCC4=CC=CC=C4)=CN1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Zamicastat (BIA 5-1058) 是多巴胺 β-羟化酶 (DBH) 抑制剂，可透过血脑屏障引起中枢和周边效应。Zamicastat 也是一种浓度依赖性的双重P-gp和BCRP抑制剂，IC50值分别为 73.8 μM 和 17.0 μM。Zamicastat 具有降血压作用。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
