KS176
Cat. No.:YN360691
CAS No. :1253452-78-6
产品名称: | KS176 |
CAS No.: | 1253452-78-6 |
Chemical Name: | N-[4-(2-hydroxyethyl)phenyl]-2-[(4-nitrobenzoyl)amino]-benzamide |
Synonyms: | KS 176;KS-176;N-[4-(2-Hydroxyethyl)phenyl]-2-[(4-nitrobenzoyl)amino]-benzamide;KS176 |
分子量: | 405.40 |
分子式: | C₂₂H₁₉N₃O₅ |
SMILES: | O=C(C1=C(NC(C2=CC=C([N+]([O-])=O)C=C2)=O)C=CC=C1)NC3=CC=C(CCO)C=C3 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | KS176是一种选择性的高活性乳腺癌耐药蛋白多药转运通道 (BCRP) 抑制剂(在Pheo A和Hoechst检测中IC50值分别为0.59和1.39 μM)。对P-gp和MRP1没有抑制活性。 |
IC50和靶点: | |
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In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: |
Pick, A., Klinkhammer, W., and Wiese, M.Specific inhibitors of the breast cancer resistance protein (BCRP)ChemMedChem5(9),1498-1505(2010)