NH125
Cat. No.：YN250033
CAS No. ：278603-08-0
| 产品名称: | NH125 |
| CAS No.: | 278603-08-0 |
| Chemical Name: | 1-hexadecyl-2-methyl-3-(phenylmethyl)-1H-imidazolium-iodide |
| Synonyms: | |
| 分子量: | 524.56 |
| 分子式: | C₂₇H₄₅IN₂ |
| SMILES: | CC1=[N+](CC2=CC=CC=C2)C=CN1CCCCCCCCCCCCCCCC.[I-] |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | NH125 是一种高效、选择性的真核延长因子 2 激酶(eEF-2K/CaMKIII)抑制剂，能够诱导 eEF2 磷酸化，对 eEF-2K 作用的IC50值为 60 nM。 |
| IC50和靶点: | [{name:"CaMK III:60 nM (IC50)"}] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Yamamoto, K., Kitayama, T., Ishida, N., et al.Identification and characterization of a potent antibacterial agent, NH125 against drug-resistant bacteriaBiosci. Biotechnol. Biochem.64(4),919-923(2000)
Yamamoto, K., Kitayama, T., Minagawa, S., et al.Antibacterial agents that inhibit histidine protein kinase YycG of Bacillus subtilisBiosci. Biotechnol. Biochem.65(10),2306-2310(2001)
Arora, S., Yang, J.M., Kinzy, T.G., et al.Identification and characterization of an inhibitor of eukaryotic elongation factor 2 kinase against human cancer cell linesCancer Res.63(20),6894-6899(2003)
