Q203
Cat. No.:YN250048
CAS No. :1334719-95-7
产品名称: | Q203 |
CAS No.: | 1334719-95-7 |
Chemical Name: | 6-chloro-2-ethyl-N-[[4-[4-[4-(trifluoromethoxy)phenyl]-1-piperidinyl]phenyl]methyl]-imidazo[1,2-a]pyridine-3-carboxamide |
Synonyms: | IAP6; Telacebec |
分子量: | 557.01 |
分子式: | C₂₉H₂₈ClF₃N₄O₂ |
SMILES: | O=C(C1=C(CC)N=C2C=CC(Cl)=CN21)NCC3=CC=C(N4CCC(C5=CC=C(OC(F)(F)F)C=C5)CC4)C=C3 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Q203(IAP6)是中氮杂吡啶酰胺化合物。 在培养基中抑制结核分枝杆菌H37Rv活性的MIC50值为2.7 nM。 |
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Pethe, K., Bifani, P., Jang, J., et al.Discovery of Q203, a potent clinical candidate for the treatment of tuberculosisNat. Med.19(9),1157-1160(2013)
Scherr, N., Bieri, R., Thomas, S.S., et al.Targeting the Mycobacterium ulcerans cytochrome bc1:aa3 for the treatment of Buruli ulcerNat. Commun.9(1),5370(2018)