Iberin
Cat. No.：YN250052
CAS No. ：505-44-2
| 产品名称: | Iberin |
| CAS No.: | 505-44-2 |
| Chemical Name: | 1-isothiocyanato-3-(methylsulfinyl)-propane |
| Synonyms: | NSC 321801 |
| 分子量: | 163.26 |
| 分子式: | C₅H₉NOS₂ |
| SMILES: | O=S(CCCN=C=S)C |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Iberin是萝卜硫素的亚砜类似物，是天然存在的异硫氰酸酯家族的成员。抑制HL60细胞的IC50值为2.3 μM。 |
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Munday, R., and Munday, C.M.Induction of phase II detoxification enzymes in rats by plant-derived isothiocyanates: Comparison of allyl isothiocyanate with sulforaphane and related compoundsJ. Agric. Food. Chem.52(7),1867-1871(2004)
La Marca, M., Beffy, P., Della Croce, C., et al.Structural influence of isothiocyanates on expression of cytochrome P450, phase II enzymes, and activation of Nrf2 in primary rat hepatocytesFood Chem. Toxicol.50(8),2822-2830(2012)
Barrera, L.N., Cassidy, A., Wang, W., et al.TrxR1 and GPx2 are potently induced by isothiocyanates and selenium, and mutually cooperate to protect Caco-2 cells against free radical-mediated cell deathBiochim. Biophys. Acta1823(10),1914-1924(2012)
Jadhav, U., Ezhilarasan, R., Vaughn, S.F., et al.Iberin induces cell cycle arrest and apoptosis in human neuroblastoma cellsInt. J. Mol. Med.19(3),353-361(2007)
Jakobsen, T.H., Bragason, S.K., Phipps, R.K., et al.Food as a source for quorum sensing inhibitors: Iberin from horseradish revealed as a quorum sensing inhibitor of Pseudomonas aeruginosaAppl. Environ. Microbiol.78(7),2410-2421(2012)
