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AAI101

Cat. No.:YN250088

  • CAS No. :1001404-83-6

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    • 生物活性
    • 参考文献
    • 产品名称: AAI101
      CAS No.: 1001404-83-6
      Chemical Name: 3-[[(2S,3S,5R)-2-carboxy-3-methyl-4,4-dioxido-7-oxo-4-thia-1-azabicyclo[3.2.0]hept-3-yl]methyl]-1-methyl-1H-1,2,3-triazolium, inner salt
      Synonyms:AAI101
      分子量:314.32
      分子式:C₁₁H₁₄N₄O₅S
      SMILES:C[N+]1=NN(C[C@@](S([C@]2([H])C3)(=O)=O)(C)[C@H](C([O-])=O)N2C3=O)C=C1
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: AAI101 是一种广谱的 β-lactamase 抑制剂,能够抵抗很多耐药革兰氏阴性细菌。
      IC50和靶点:
      In Vitro:
      In Vivo:
      Clinical Trial:
      Solvent & Solubility:
    • Papp-Wallace, K.M., Bethel, C.R., Caillon, J., et al.Beyond piperacillin-tazobactam: Cefepime and AAI101 as a potent β-lactam-β-lactamase inhibitor combinationAntimicrob Agents Chemother.63(5),e00105-00119(2019)

      Crandon, J.L., and Nicolau, D.P.In vitro activity of cefepime/AAI101 and comparators against cefepime non-susceptible EnterobacteriaceaePathogens4(3),620-625(2015)

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