TBAJ-587
Cat. No.：YN250203
CAS No. ：2252316-16-6
| 产品名称: | TBAJ-587 |
| CAS No.: | 2252316-16-6 |
| Chemical Name: | |
| Synonyms: | TBAJ587;TBAJ 587;BCP31090;(1S,2S)-1-(6-Bromo-2-methoxyquinolin-3-yl)-2-(2,6-dimethoxypyridin-4-yl)-4-(dimethylamino)-1-(2-fluoro-3-methoxyphenyl)butan-2-ol;CID 138319677;TBAJ-587 |
| 分子量: | 614.50 |
| 分子式: | C₃₀H₃₃BrFN₃O₅ |
| SMILES: | COC1=C(F)C([C@H](C2=CC3=CC(Br)=CC=C3N=C2OC)[C@](O)(C4=CC(OC)=NC(OC)=C4)CCN(C)C)=CC=C1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | TBAJ-587 是一种有效的抗结核药物，在 MABA 和 LORA 实验中抑制M.tb菌株 H37Rv 生长MIC90分别为 0.006 和 <0.02 μg/mL。TBAJ-587 对 hERG 通道的抑制作用很低，大大减弱了对心脏钾通道蛋白的抑制，这对心脏复极化很重要。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
