4-(tert-Butyl)-benzhydroxamic Acid
Cat. No.:YN250240
CAS No. :62034-73-5
产品名称: | 4-(tert-Butyl)-benzhydroxamic Acid |
CAS No.: | 62034-73-5 |
Chemical Name: | 4-(1,1-Dimethylethyl)-N-hydroxybenzamide; |
Synonyms: | |
分子量: | 193.24 |
分子式: | C₁₁H₁₅NO₂ |
SMILES: | O=C(C1=CC=C(C=C1)C(C)(C)C)NO |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | 4-(tert-Butyl)-benzhydroxamic Acid 是一种PqsR拮抗剂,在大肠杆菌和铜绿假单胞菌中IC50值分别为 12.5 μM 和 23.6 μM。4-(tert-Butyl)-benzhydroxamic Acid 可以降低铜绿假单胞菌毒力因子绿脓素的产量,IC50为 87.2 μM。 |
IC50和靶点: | |
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Klein, T. et al.: ACS Chem. Biol., 7, 1496 (2012)
Siliphaivanh, P. et al.: Bioorg. Med. Chem. Lett., 17, 4619 (2007)