Bisdionin C
Cat. No.：YN250247
CAS No. ：74857-22-0
| 产品名称: | Bisdionin C |
| CAS No.: | 74857-22-0 |
| Chemical Name: | 1,1'-(1,3-Propanediyl)bis[3,7-dihydro-3,7-dimethyl-1H-purine-2,6-dione]; 1,1'-Trimethylenedi-theobromine; |
| Synonyms: | |
| 分子量: | 400.39 |
| 分子式: | C₁₇H₂₀N₈O₄ |
| SMILES: | O=C(N1CCCN2C(N(C)C3=C(N(C)C=N3)C2=O)=O)N(C)C4=C(N(C)C=N4)C1=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Bisdionin C 是一种高效的GH18几丁质酶抑制剂，对A. fumigatusChiB1 (AfChiB1) 的 IC50为 0.2 μM。Bisdionin C 对 HCHT (human macrophage chitotriosidase) 和酸性哺乳动物几丁质酶 (AMCase) 的抑制作用分别为 8.3 和 3.4 μM。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
Suto, M., et al.: Anticancer Drug Des., 6, 107 (1991), Burkart, V., et al.: Nat. Med., 5, 314 (1999), Hassa, P., et al.: J. Biol. Chem., 278, 45145 2003), Veres, B., et al.: J. Pharmacol. Exp. Ther., 310, 247(2004)
