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Indolmycin

Cat. No.:YN250267

  • CAS No. :21200-24-8

    • 产品资料
    • 生物活性
    • 参考文献
    • 产品名称: Indolmycin
      CAS No.: 21200-24-8
      Chemical Name: 5S-[(1R)-1-(1H-indol-3-yl)ethyl]-2-(methylamino)-4(5H)-oxazolone
      Synonyms:TAK-083; PA-155A
      分子量:257.29
      分子式:C₁₄H₁₅N₃O₂
      SMILES:O=C1N=C(NC)O[C@H]1[C@@H](C2=CNC3=C2C=CC=C3)C
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: Indolmycin (TAK-083) 是一种抗生素,是原核生物色氨酸-tRNA 连接酶(TrpS)的竞争性抑制剂。Indolmycin (TAK-083) 具有抗菌和抗病毒活性。
      IC50和靶点:
      In Vitro:
      In Vivo:
      Clinical Trial:
      Solvent & Solubility:
    • Werner, R.G., Thorpe, L.F., Reuter, W., et al.Indolmycin inhibits prokaryotic tryptophanyl-tRNA ligaseEur. J. Biochem.68(1),1-3(1976)

      Bogosian, G., Haydock, P.V., and Somerville, R.L.Indolmycin-mediated inhibition and stimulation of transcription at the trp promoter of Escherichia coliJ. Bacteriol.153(2),1120-1123(1983)

      Hurdle, J.G., O'Neill, A.J., and Chopra, I.Anti-staphylococcal activity of indolmycin, a potential topical agent for control of staphylococcal infectionsJ. Antimicrob. Chemother.52(4),549-552(2004)

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