Indolmycin
Cat. No.:YN250267
产品名称: | Indolmycin |
CAS No.: | 21200-24-8 |
Chemical Name: | 5S-[(1R)-1-(1H-indol-3-yl)ethyl]-2-(methylamino)-4(5H)-oxazolone |
Synonyms: | TAK-083; PA-155A |
分子量: | 257.29 |
分子式: | C₁₄H₁₅N₃O₂ |
SMILES: | O=C1N=C(NC)O[C@H]1[C@@H](C2=CNC3=C2C=CC=C3)C |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Indolmycin (TAK-083) 是一种抗生素,是原核生物色氨酸-tRNA 连接酶(TrpS)的竞争性抑制剂。Indolmycin (TAK-083) 具有抗菌和抗病毒活性。 |
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Werner, R.G., Thorpe, L.F., Reuter, W., et al.Indolmycin inhibits prokaryotic tryptophanyl-tRNA ligaseEur. J. Biochem.68(1),1-3(1976)
Bogosian, G., Haydock, P.V., and Somerville, R.L.Indolmycin-mediated inhibition and stimulation of transcription at the trp promoter of Escherichia coliJ. Bacteriol.153(2),1120-1123(1983)
Hurdle, J.G., O'Neill, A.J., and Chopra, I.Anti-staphylococcal activity of indolmycin, a potential topical agent for control of staphylococcal infectionsJ. Antimicrob. Chemother.52(4),549-552(2004)