MreB Perturbing Compound A22 hydrochloride
Cat. No.：YN250273
| 产品名称: | MreB Perturbing Compound A22 hydrochloride |
| CAS No.: | 22816-60-0 |
| Chemical Name: | carbamimidothioic acid,(3,4-dichlorophenyl)methyl ester, monohydrochloride |
| Synonyms: | A22 hydrochloride |
| 分子量: | 271.59 |
| 分子式: | C₈H₉Cl₃N₂S |
| SMILES: | ClC1=CC(CSC(N)=N)=CC=C1Cl.Cl |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | MreB Perturbing Compound A22 (hydrochloride) is a benzylisothiourea compound that interacts with the ATP binding site of MreB rapidly and reversibly. MreB Perturbing Compound A22 (hydrochloride) blocks normal rod shape formation and inhibits chromosome pa |
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Doi, M., Wachi, M., Ishino, F., et al.Determinations of the DNA sequence of the mreB gene and of the gene products of the mre region that function in formation of the rod shape of Escherichia coli cellsJ. Bacteriol.170(10),4619-4624(1988)
Tan, Q., Awano, N., and Inouye, M.YeeV is an Escherichia coli toxin that inhibits cell division by targeting the cytoskeleton proteins, FtsZ and MreBMol. Microbiol.79(1),109-118(2011)
Gitai, Z., Dye, N.A., Reisenauer, A., et al.MreB actin-mediated segregation of a specific region of a bacterial chromosomeCell120(3),329-341(2005)
Iwai, N., Nagai, K., and Wachi, M.Novel S-benzylisothiourea compound that induces spherical cells in Escherichia coli probably by acting on a rod-shape-determining protein(s) other than penicillin-binding protein 2Biosci. Biotechnol. Biochem.66(12),2658-2662(2002)
Srivastava, P.Changes in nucleoid morphology and origin localization upon inhibition or alteration of the actin homolog, MreB, of Vibrio choleraeJ. Bacteriol.189(20),7450-7463(2007)
