Kirromycin
Cat. No.：YN250325
CAS No. ：50935-71-2
| 产品名称: | Kirromycin |
| CAS No.: | 50935-71-2 |
| Chemical Name: | (αS,2R,3R,4R,6S)-N-[(2E,4E,6S,7R)-7-[(2S,3S,4R,5R)-5-[(1E,3E,5E)-7-(1,2-dihydro-4-hydroxy-2-oxo-3-pyridinyl)-6-methyl-7-oxo-1,3,5-heptatrien-1-yl]tetrahydro-3,4-dihydroxy-2-furanyl]-6-methoxy-5-methyl-2,4-octadien-1-yl]-α-ethyltetrahydro-2,3,4-trihydroxy- |
| Synonyms: | Mocimycin; Delvomycin |
| 分子量: | 796.94 |
| 分子式: | C₄₃H₆₀N₂O₁₂ |
| SMILES: | O=C(NC/C=C/C=C(C)/[C@@H](OC)[C@H]([C@]([C@H]([C@H]1O)O)([H])O[C@@H]1/C=C/C=C/C=C(C)/C(C(C2=O)=C(C=CN2)O)=O)C)[C@H]([C@@](O[C@H](C(C)3C)/C=C/C=C\C)([C@@H]([C@@H]3O)O)O)CC |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Kirromycin (Mocimycin) 是一种由链霉菌 (Streptomyces ramocissimus) 生产的抗生素。Kirromycin 是一种细菌蛋白合成 (bacterial protein synthesis) 抑制剂，可将延长因子 Tu (EF-Tu) 固定在延长的核糖体上。 |
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Wolf, H., Zähner, H., and Nierhaus, K.Kirromycin, an inhibitor of the 30 S ribosomal subunits functionFEBS Lett.21(3),347-350(1972)
Wolf, H., Chinali, G., and Parmeggiani, A.Kirromycin, an inhibitor of protein biosynthesis that acts on elongation factor TuProc. Natl. Acad. Sci. USA71(12),4910-4914(1974)
