ULS 欢迎您!
ULS 欢迎您!
> 产品中心 > 抑制剂 & 激动剂 > Anti-infection > Bacterial

Ionomycin calcium

Cat. No.:YN250480

  • CAS No. :56092-82-1

    • 产品资料
    • 生物活性
    • 参考文献
    • 产品名称: Ionomycin calcium
      CAS No.: 56092-82-1
      Chemical Name: 11,19R,21S-trihydroxy-4R,6S,8S,12R,14R,18R,20S-heptamethyl-22-[octahydro-5'S-[1R-hydroxyethyl]-2S,5'-dimethyl[2,2'R-bifuran]-5S-yl]-9-oxo-10Z,16E-docosadienoic acid, calcium salt
      Synonyms:SQ23377 calcium
      分子量:747.07
      分子式:C₄₁H₇₀CaO₉
      SMILES:O=C([O-])CC[C@@H](C)C[C@H](C)C[C@H](C)C(/C=C([O-])/[C@H](C)C[C@H](C)C/C=C/[C@@H](C)[C@@H](O)[C@@H](C)[C@@H](O)C[C@@H]1CC[C@]([C@@H]2O[C@](C)([C@H](O)C)CC2)(C)O1)=O.[Ca+2]
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
      Select Batch:
      Purity: 98%
    • 产品描述: Ionomycin calcium (SQ23377 calcium) 是一种有效的,选择性的钙离子载体(calcium ionophore),也是一种由Streptomyces conglobatus产生的抗生素。Ionomycin calcium (SQ23377 calcium) 对二价阳离子具有高度特异性 (Ca>Mg>Sr=Ba)。Ionomycin (SQ23377) 促进细胞凋亡。Ionomycin calcium (SQ23377 calcium) 还诱导蛋白激酶C (PKC) 激活。
      IC50和靶点:
      In Vitro:
      In Vivo:
      Clinical Trial:
      Solvent & Solubility:
    • Liu, W.C., Slusarchyk, D.S., Astle, G., et al.Ionomycin, a new polyether antibioticJ. Antibiot. (Tokyo)31(9),815-819(1978)

      Locke, M., Francis, R.J., Tsaousi, E., et al.Fibrinogen protects neutrophils from the cytotoxic effects of histones and delays neutrophil extracellular trap formation induced by ionomycinSci. Rep.10(1),11694(2020)

      Lehnert, C., Weiswange, M., Jeremias, I., et al.TRAIL-receptor costimulation inhibits proximal TCR signaling and suppresses human T cell activation and proliferationJ. Immunol.193(8),4021-4031(2014)

      Foey, A.D., and Brennan, F.M.Conventional protein kinase C and atypical protein kinase Cζ differentially regulate macrophage production of tumour necrosis factor-ɑ and interleukin-10Immunology112(1),44-53(2004)

    • 摩尔计算器
    • 稀释计算器
    摩尔浓度计算器方程 :
    Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

    计算

    质量 浓度 体积 分子量
    稀释计算器 :
    Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)
    • C1
      V1
      C2
      V2
    • 您最近查看的产品:
    相关产品


    ULS 的所有产品和服务仅用于科学研究,我们不为任何其他用途提供产品和服务(也不为任何个人提供产品和服务)Copyright © 2020-2021 ULS. All Rights Reserved. 备案号:粤ICP备2021013238号-1
    0.336107s