Hydroxymetronidazole
Cat. No.：YN250536
CAS No. ：4812-40-2
| 产品名称: | Hydroxymetronidazole |
| CAS No.: | 4812-40-2 |
| Chemical Name: | 2-(hydroxymethyl)-5-nitro-1H-imidazole-1-ethanol |
| Synonyms: | Metronidazole-OH |
| 分子量: | 187.15 |
| 分子式: | C₆H₉N₃O₄ |
| SMILES: | OCCN1C([N+]([O-])=O)=CN=C1CO |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Hydroxymetronidazole (Metronidazole-OH) 是一种 Metronidazole 的代谢产物，属于硝基咪唑类。Hydroxymetronidazole 可用于研究家禽中的某些细菌和原生动物疾病，以及牛痢疾和牛生殖器滴虫病。 |
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Pendland, S.L., Piscitelli, S.C., Schreckenberger, P.C., et al.In vitro activities of metronidazole and its hydroxy metabolite against Bacteroides sppAntimicrob. Agents Chemother.38(9),2106-2110(1994)
Pearce, R.E., Cohen-Wolkowiez, M., Sampson, M.R., et al.The role of human cytochrome P450 enzymes in the formation of 2-hydroxymetronidazole: CYP2A6 is the high affinity (low Km) catalystDrug Metab. Dispos.41(9),1686-1694(2013)
Tölgyesi, A., Sharma, V.K., Fekete, S., et al.Development of a rapid method for the determination and confirmation of nitroimidazoles in six matrices by fast liquid chromatography-tandem mass spectrometryJ. Pharm. Biomed. Anal.64-65,40-48(2012)
