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Lansoprazole

Cat. No.:YN250551

  • CAS No. :103577-45-3

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    • 参考文献
    • 产品名称: Lansoprazole
      CAS No.: 103577-45-3
      Chemical Name: 2-[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]sulfinyl]-1H-benzimidazole
      Synonyms:兰索拉唑; AG-1749
      分子量:369.36
      分子式:C₁₆H₁₄F₃N₃O₂S
      SMILES:O=S(C1=NC2=CC=CC=C2N1)CC3=NC=CC(OCC(F)(F)F)=C3C
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: Lansoprazole (AG 1749) 是质子泵抑制剂,能抑制胃酸生成。Lansoprazole (AG 1749) 是中性鞘磷脂酶(N-SMase)的抑制剂(外泌体抑制剂)。
      IC50和靶点:
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    • Nagaya, H., Satoh, H., Kubo, K., et al.Possible mechanism for the inhibition of gastric (H+ + K+)-adenosine triphosphatase by the proton pump inhibitor AG-1749J. Pharmacol. Exp. Ther.248(2),799-805(1989)

      Schubert, M.L.Pharmacotherapy for acid/peptic disordersYale J. Biol. Med.69(2),197-201(1996)

      Richardson, P., Hawkey, C.J., and Stack, W.A.Proton pump inhibitors. Pharmacology and rationale for use in gastrointestinal disordersDrugs56(3),307-335(1998)

      Klotz, U.Pharmacokinetic considerations in the eradication of Helicobacter pyloriClin. Pharmacokinet.38(3),243-270(2000)

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