Meropenem trihydrate
Cat. No.:YN250555
产品名称: | Meropenem trihydrate |
CAS No.: | 119478-56-7 |
Chemical Name: | (4R,5S,6S)-3-[[(3S,5S)-5-[(dimethylamino)carbonyl]-3-pyrrolidinyl]thio]-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid, trihydrate |
Synonyms: | 三水合美罗培南; SM 7338 trihydrate |
分子量: | 437.51 |
分子式: | C₁₇H₃₁N₃O₈S |
SMILES: | O=C(C(N12)=C(S[C@@H]3CN[C@H](C(N(C)C)=O)C3)[C@H](C)[C@]2([H])[C@@H]([C@H](O)C)C1=O)O.O.O.O |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Meropenem trihydrate (SM 7338 trihydrate) 是一种具有广谱抗菌活性的碳青霉烯抗生素。Meropenem trihydrate 对敏感和耐药的淋病奈瑟氏球菌 (MIC 值为 0.02-0.06 mg/mL),流感嗜血杆菌 (MIC 值为 0.03-0.12 mg/mL) 和杜克氏杆菌 (MIC 值为 0.015-0.12 mg/mL) 具有活性。 |
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Edwards, J.R., Turner, P.J., Wannop, C., et al.In vitro antibacterial activity of SM-7338, a carbapenem antibiotic with stability to dehydropeptidase IAntimicrob. Agents Chemother.33(2),215-222(1989)
Edwards, J.R., Williams, S., and Nairn, K.Therapeutic activity of meropenem in experimental infectionsJ. Antimicrob. Chemother.24(Suppl. A),279-285(1989)