Delafloxacin
Cat. No.：YN250600
| 产品名称: | Delafloxacin |
| CAS No.: | 189279-58-1 |
| Chemical Name: | 1-(6-amino-3,5-difluoro-2-pyridinyl)-8-chloro-6-fluoro-1,4-dihydro-7-(3-hydroxy-1-azetidinyl)-4-oxo-3-quinolinecarboxylic acid |
| Synonyms: | 德拉沙星; RX-3341; WQ-3034; ABT492 |
| 分子量: | 440.76 |
| 分子式: | C₁₈H₁₂ClF₃N₄O₄ |
| SMILES: | O=C(C1=CN(C2=NC(N)=C(F)C=C2F)C3=C(C=C(F)C(N4CC(O)C4)=C3Cl)C1=O)O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Delafloxacin (RX-3341; WQ-3034; ABT492) 是一种广谱氟喹诺酮类抗生素。Delafloxacin 具有广泛的活性，对耐药性的金黄色葡萄球菌，肺炎链球菌和肺炎克雷伯菌都有效。 |
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Goldstein, E.J.C., Citron, D.M., Merriam, C.V., et al.In vitro activities of ABT-492, a new fluoroquinolone, against 155 aerobic and 171 anaerobic pathogens isolated from antral sinus puncture specimens from patients with sinusitisAntimicrob. Agents Chemother.47(9),3008-3011(2003)
Nilius, A.M., Shen, L.L., Hensey-Rudloff, D., et al.In vitro antibacterial potency and spectrum of ABT-492, a new fluoroquinoloneAntimicrob. Agents Chemother.47(10),3260-3269(2003)
Kocsis, B., Domokos, J., and Szabo, D.Chemical structure and pharmacokinetics of novel quinolone agents represented by avarofloxacin, delafloxacin, finafloxacin, zabofloxacin and nemonoxacinAnn. Clin. Microbiol. Antimicrob.15(1),34(2016)
