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Delafloxacin meglumine

Cat. No.:YN250601

  • CAS No. :352458-37-8

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    • 生物活性
    • 参考文献
    • 产品名称: Delafloxacin meglumine
      CAS No.: 352458-37-8
      Chemical Name: 1-deoxy-1-(methylamino)-D-glucitol, 1-(6-amino-3,5-difluoro-2-pyridinyl)-8-chloro-6-fluoro-1,4-dihydro-7-(3-hydroxy-1-azetidinyl)-4-oxo-3-quinolinecarboxylate (1:1)
      Synonyms:德拉沙星葡甲胺; ABT492 meglumine; RX-3341 meglumine; WQ-3034 meglumine
      分子量:635.97
      分子式:C₂₅H₂₉ClF₃N₅O₉
      SMILES:O=C(C1=CN(C2=NC(N)=C(F)C=C2F)C3=C(C=C(F)C(N4CC(O)C4)=C3Cl)C1=O)O.O[C@H]([C@H]([C@@H]([C@@H](CO)O)O)O)CNC
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
      Select Batch:
      Purity: 98%
    • 产品描述: Delafloxacin meglumine (ABT492 meglumine; RX-3341 meglumine; WQ-3034 meglumine) 是一种广谱氟喹诺酮类抗生素。Delafloxacin 具有广泛的活性,对耐药性的金黄色葡萄球菌,肺炎链球菌和肺炎克雷伯菌都有效。
      IC50和靶点:
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    • Nilius, A.M., Shen, L.L., Hensey-Rudloff, D., et al.In vitro antibacterial potency and spectrum of ABT-492, a new fluoroquinoloneAntimicrob. Agents Chemother.47(10),3260-3269(2003)

      Lepak, A.J., and Andes, D.R.In vivo pharmacodynamic target assessment of delafloxacin against Staphylococcus aureus, Streptococcus pneumoniae, and Klebsiella pneumoniae in a murine lung infection modelAntimicrob. Agents Chemother.60(8),4764-4769(2016)

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