Tedizolid
Cat. No.：YN250604
| 产品名称: | Tedizolid |
| CAS No.: | 856866-72-3 |
| Chemical Name: | (5R)-3-[3-fluoro-4-[6-(2-methyl-2H-tetrazol-5-yl)-3-pyridinyl]phenyl]-5-(hydroxymethyl)-2-oxazolidinone |
| Synonyms: | 特地唑胺; TR 700; Torezolid; DA-7157 |
| 分子量: | 370.34 |
| 分子式: | C₁₇H₁₅FN₆O₃ |
| SMILES: | O=C1O[C@@H](CO)CN1C2=CC=C(C3=CC=C(C4=NN(C)N=N4)N=C3)C(F)=C2 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Tedizolid (TR 700; Torezolid; DA-7157) 是一种新型恶唑烷酮，通过与核糖体50S亚基的23S核糖体RNA结合来抑制细菌 (bacterial) 的蛋白质合成。 |
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Schaadt, R., Sweeney, D.A., Shinabarger, D., et al.In vitro activity of TR-700, the active ingredient of the antibacterial prodrug TR-701, a novel oxazolidinone antibacterial agentAntimicrob. Agents Chemother.53(8),3236-3239(2009)
Im, W.B., Choi, S.H., Park, J.-Y., et al.Discovery of torezolid as a novel 5-hydroxymethyl-oxazolidinone antibacterial agentEur. J. Med. Chem.46(4),1027-1039(2011)
