Bedaquiline
Cat. No.：YN250610
CAS No. ：843663-66-1
| 产品名称: | Bedaquiline |
| CAS No.: | 843663-66-1 |
| Chemical Name: | (αS,βR)-6-bromo-α-[2-(dimethylamino)ethyl]-2-methoxy-α-1-naphthalenyl-β-phenyl-3-quinolineethanol |
| Synonyms: | 贝达喹啉; TMC207; R207910 |
| 分子量: | 555.50 |
| 分子式: | C₃₂H₃₁BrN₂O₂ |
| SMILES: | BrC1=CC=C(N=C(OC)C([C@H]([C@@](C2=CC=CC3=C2C=CC=C3)(O)CCN(C)C)C4=CC=CC=C4)=C5)C5=C1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Bedaquiline (TMC207) 是一种二芳基喹啉药物，通过同时靶向 c-亚基和 ε-亚基来抑制结核分枝杆菌 (Mtb) F1FO-ATP合酶。Bedaquiline 具有解偶联活性。Bedaquiline 有用于耐多药结核病的潜力。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
Matteelli, A., Carvalho, A.C.C., Dooley, K.E., et al.TMC207: The first compound of a new class of potent anti-tuberculosis drugsFuture Microbiol.5(6),849-858(2010)
