Rifabutin
Cat. No.：YN250695
| 产品名称: | Rifabutin |
| CAS No.: | 72559-06-9 |
| Chemical Name: | (9S,12E,14S,15R,16S,17R,18R,19R,20S,21S,22E,24Z)-16-(acetyloxy)-6,18,20-trihydroxy-14-methoxy-7,9,15,17,19,21,25-heptamethyl-1’-(2-methylpropyl)-spiro[9,4-(epoxypentadeca[1,11,13]trienimino)-2H-furo[2’,3’:7,8]naphth[1,2-d]imidazole-2,4’-piperidine]-5,10,2 |
| Synonyms: | 利福布丁; Ansamycin; LM-427 |
| 分子量: | 847.00 |
| 分子式: | C₄₆H₆₂N₄O₁₁ |
| SMILES: | C[C@@]1(O2)O/C=C/[C@@H]([C@H]([C@H]([C@H](C)[C@H](O)[C@H](C)[C@H]([C@H](/C=C/C=C(C(NC(C3=O)=C4NC5(CCN(CC(C)C)CC5)N=C4C6=C3C(O)=C(C)C2=C6C1=O)=O)\C)C)O)OC(C)=O)C)OC |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Rifabutin (Ansamycin) 是半合成的安莎霉素抗生素，具有抗分枝杆菌特性。Rifabutin 抑制 DNA 依赖性 RNA 聚合酶。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
Heep, M., Beck, D., Bayerdörffer, E., et al.Rifampin and rifabutin resistance mechanism in Helicobacter pyloriAntimicrob. Agents Chemother.43(6),1497-1499(1999)
Kunin, C.M.Antimicrobial activity of rifabutinClin. Infect. Dis.22(Supp. 1),S3-S14(1996)
Klemens, S.P., Grossi, M.A., and Cynamon, M.H.Comparative in vivo activities of rifabutin and rifapentine against Mycobacterium avium complexAntimicrob. Agents Chemother.38(2),(1994)
