Besifloxacin Hydrochloride
Cat. No.：YN250696
CAS No. ：405165-61-9
| 产品名称: | Besifloxacin Hydrochloride |
| CAS No.: | 405165-61-9 |
| Chemical Name: | 7-[(3R)-3-aminohexahydro-1H-azepin-1-yl]-8-chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid, monohydrochloride |
| Synonyms: | Besifloxacin HCl,BOL-303224-A,Besivance hydrochloride,盐酸贝西沙星 |
| 分子量: | 430.30 |
| 分子式: | C₁₉H₂₂Cl₂FN₃O₃ |
| SMILES: | O=C(C1=CN(C2CC2)C3=C(C=C(F)C(N4C[C@H](N)CCCC4)=C3Cl)C1=O)O.[H]Cl |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Besifloxacin Hydrochloride 是第四代氟喹诺酮类抗生素。 |
| IC50和靶点: | |
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Ward, K.W., Lepage, J.F., and Driot, J.Y.Nonclinical pharmacodynamics, pharmacokinetics, and safety of BOL-303224-A, a novel fluoroquinolone antimicrobial agent for topical ophthalmic useJ. Ocul. Pharmacol. Ther.23(3),243-256(2007)
Zhang, J.-Z., and Ward, K.W.Besifloxacin, a novel fluoroquinolone antimicrobial agent, exhibits potent inhibition of pro-inflammatory cytokines in human THP-1 monocytesJ. Antimicrob. Chemother.61(1),111-116(2008)
Norcross, E.W., Sanders, M.E., Moore, Q., III, et al.Comparative efficacy of besifloxacin and other fluoroquinolones in a prophylaxis model of penicillin-resistant Streptococcus pneumoniae rabbit endophthalmitisJ. Ocul. Pharmacol. Ther.26(3),237-243(2010)
