Acyclovir
Cat. No.：YN250714
| 产品名称: | Acyclovir |
| CAS No.: | 59277-89-3 |
| Chemical Name: | 2-amino-1,9-dihydro-9-[(2-hydroxyethoxy)methyl]-6H-purin-6-one |
| Synonyms: | 阿昔洛韦; Aciclovir; Acycloguanosine |
| 分子量: | 225.20 |
| 分子式: | C₈H₁₁N₅O₃ |
| SMILES: | O=C1NC(N)=NC2=C1N=CN2COCCO |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Acyclovir (Aciclovir) 是一种鸟嘌呤类似物和一种具有口服活性的抗病毒剂。Acyclovir 具有抗HSV-1(IC50为 0.85 μM)，HSV-2(IC50为 0.86 μM) 和水痘带状疱疹病毒的活性。Acyclovir 可被病毒胸苷激酶 (TK) 磷酸化，Acyclovir triphosphate 可干扰病毒 DNA 聚合。Acyclovir 可预防急性白血病的诱导疗法中的细菌感染。 |
| IC50和靶点: | [{name:"HSV-1:0.85 μM (IC50)"},{name: "HSV-2:0.86 μM (IC50)"}] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Balfour, H.H., Jr.Management of cytomegalovirus disease with antiviral drugsRev. Infect. Dis.12(Suppl. 7),S849-S860(1990)
Bean, B.Antiviral therapy: Current concepts and practicesClin. Microbiol. Rev.5(2),146-182(1992)
Ashton, R.J., Abbott, K.H., Smith, G.M., et al.Antiviral activity of famciclovir and acyclovir in mice infected intraperitoneally with herpes simplex virus type 1 SC16J. Antimicrob. Chemother.34(2),287-290(1994)
