Garenoxacin
Cat. No.：YN250729
| 产品名称: | Garenoxacin |
| CAS No.: | 194804-75-6 |
| Chemical Name: | 1-cyclopropyl-8-(difluoromethoxy)-7-[(1R)-2,3-dihydro-1-methyl-1H-isoindol-5-yl]-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid |
| Synonyms: | 加雷沙星; BMS284756 |
| 分子量: | 426.41 |
| 分子式: | C₂₃H₂₀F₂N₂O₄ |
| SMILES: | O=C(C1=CN(C2CC2)C3=C(C=CC(C4=CC5=C([C@@H](C)NC5)C=C4)=C3OC(F)F)C1=O)O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Garenoxacin (BMS284756) 是一种新型的口服 des-fluoro(6) 喹诺酮, 具有强的抗菌活性, 抗常见呼吸道病原体, 包括耐药菌株。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Takahata, M., Mitsuyama, J., Yamashiro, Y., et al.In vitro and in vivo antimicrobial activities of T-3811ME, a novel des-F(6)-quinoloneAntimicrob. Agents Chemother.43(5),1077-1084(1999)
Lawrence, L.E., Wu, P., Fan, L., et al.The inhibition and selectivity of bacterial topoisomerases by BMS-284756 and its analoguesJ. Antimicrob. Chemother.48(2),195-201(2001)
