Sancycline
Cat. No.：YN250731
CAS No. ：808-26-4
| 产品名称: | Sancycline |
| CAS No.: | 808-26-4 |
| Chemical Name: | 4-(dimethylamino)-1,4S,4aS,5,5aR,6,11,12aS-octahydro-3,10,12,12a-tetrahydroxy-1,11-dioxo-2-naphthacenecarboxamide |
| Synonyms: | 山环素; Bonomycin; 6-Demethyl-6-deoxytetracycline |
| 分子量: | 414.41 |
| 分子式: | C₂₁H₂₂N₂O₇ |
| SMILES: | O=C(C(C1=O)=C(O)[C@@H](N(C)C)[C@]2([H])C[C@]3([H])CC4=C(C(C3=C(O)[C@@]21O)=O)C(O)=CC=C4)N |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Sancycline是由Declomycin的氯和苄羟基基团经过氢热解制得的一种半合成四环素。 |
| IC50和靶点: | |
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McCormick, J.R.D., Jensen, E.R., Miller, P.A., et al.The 6-deoxytetracyclines. Further studies on the relationship between structure and antibacterial activity in the tetracycline seriesJ. Am. Chem. Soc.82(13),3381-3386(1960)
Wexler, H.M., Molitoris, E., and Finegold, S.M.In vitro activities of two new glycylcyclines, N,N-dimethylglycylamido derivatives of minocycline and 6-demethyl-6-deoxytetracycline, against 339 strains of anaerobic bacteriaAntimicrob. Agents Chemother.38(10),2513-2515(1994)
Testa, R.T., Perterson, P.J., Jacobus, N.V., et al.In vitro and in vivo antibacterial activities of the glycylcyclines, a new class of semisynthetic tetracyclinesAntimicrob. Agents Chemother.37(11),2270-2277(1993)
