Clarithromycin
Cat. No.：YN250735
| 产品名称: | Clarithromycin |
| CAS No.: | 81103-11-9 |
| Chemical Name: | 6-O-methyl-erythromycin |
| Synonyms: | 克拉霉素 |
| 分子量: | 747.95 |
| 分子式: | C₃₈H₆₉NO₁₃ |
| SMILES: | C[C@@](OC)(C[C@H](C([C@@H]1C)=O)C)[C@@H]([C@H]([C@@H]([C@H](C(O[C@H](CC)[C@@](C)(O)[C@@H]1O)=O)C)O[C@@](O[C@@H](C)[C@@H]2O)([H])C[C@@]2(C)OC)C)O[C@@](O[C@H](C)C[C@@H]3N(C)C)([H])[C@@H]3O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Clarithromycin是大环内脂类抗生素，还是CYP3A4抑制剂。 |
| IC50和靶点: | |
| In Vitro: | |
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| Solvent & Solubility: |
Hardy, D.J., Hensey, D.M., Beyer, J.M., et al.Comparative in vitro activities of new 14-, 15-, and 16-membered macrolidesAntimicrob. Agents Chemother.32(11),1710-1719(1988)
Wilson, D.N.The A-Z of bacterial translation inhibitorsCrit. Rev. Biochem. Mol. Biol.44(6),393-433(2009)
Wu, J., Kinoshita, K., Khosla, C., et al.Biochemical analysis of the substrate specificity of the β-ketoacyl-acyl carrier protein synthase domain of module 2 of the erythromycin polyketide synthaseBiochemistry43(51),16301-16310(2004)
Fernandes, P.B., Hardy, D.J., McDaniel, D., et al.In vitro and in vivo activities of clarithromycin against Mycobacterium aviumAntimicrob. Agents Chemother.33(9),1531-1534(1989)
