Capreomycin sulfate
Cat. No.：YN250752
CAS No. ：1405-37-4
| 产品名称: | Capreomycin sulfate |
| CAS No.: | 1405-37-4 |
| Chemical Name: | (2S)-2,5-diamino-N-(((2S,5R,11S,15R,Z)-15-amino-11-(2-amino-3,4,5,6-tetrahydropyrimidin-4-yl)-2-(hydroxymethyl)-3,6,9,12,16-pentaoxo-8-(ureidomethylene)-1,4,7,10,13-pentaazacyclohexadecan-5-yl)methyl)pentanamide, monosulfate |
| Synonyms: | 硫酸卷曲霉素 |
| 分子量: | 750.78 |
| 分子式: | C₂₅H₄₆N₁₄O₁₁S |
| SMILES: | O=C(CC(N)CCCN)NCC(C(N/C(C(NC(C1NC(NCC1)=N)C2=O)=O)=C/NC(N)=O)=O)NC(C(NC(C(CN2)N)=O)C)=O.O=S(O)(O)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Capreomycin sulfate 是多肽类抗生素，与其它抗生素结合用于MDR-肺结核。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
Arbex, M.A., de Castro Lima Varella, M., de Siqueira, H.R., et al.Antituberculosis drugs: Drug interactions, adverse effects, and use in special situations. Part 2: Second line drugsJ. Bras. Pneumol.36(5),641-656(2010)
Vianna, J.F., Bezerra, K.S., Oliveira, J.I.N., et al.Binding energies of the drugs capreomycin and streptomycin in complex with tuberculosis bacterial ribosome subunitsPhys. Chem. Chem. Phys.21(35),19192-19200(2019)
Sutton, W.B., Gordee, R.S., Wick, W.E., et al.In vitro and in vivo laboratory studies on the antituberculous activity of capreomycinAnn. N. Y. Acad. Sci.135(2),947-959(1966)
