Thio-TEPA
Cat. No.:YN250753
产品名称: | Thio-TEPA |
CAS No.: | 52-24-4 |
Chemical Name: | 1,1',1''-phosphinothioylidynetris-aziridine |
Synonyms: | Tiofosyl, Tiofosfamid, Triethylenethiophosphoramide |
分子量: | 189.22 |
分子式: | C₆H₁₂N₃PS |
SMILES: | S=P(N1CC1)(N2CC2)N3CC3 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Thio-TEPA 是一种 DNA 烷化剂 (DNA alkylator),具有抗肿瘤作用。 |
IC50和靶点: | |
In Vitro: | |
In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: |
Miller, B., Tenenholz, T., Egorin, M.J., et al.Cellular pharmacology of N,N',N''-triethylene thiophosphoramideCancer Lett.41(2),157-168(1988)
Maanen, M.J., Smeets, C.J., and Beijnen, J.H.Chemistry, pharmacology and pharmacokinetics of N,N′,N′′-triethylenethiophosphoramide (ThioTEPA)Cancer Treat. Rev.26(4),257-268(2000)
Kramer, W.M., and Schatten, W.E.An experimental study of triethylenethiophosphoramide (TSPA) in the prevention of postoperative pulmonary metastasesCancer11(3),463-465(1958)