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Thio-TEPA

Cat. No.:YN250753

  • CAS No. :52-24-4

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    • 生物活性
    • 参考文献
    • 产品名称: Thio-TEPA
      CAS No.: 52-24-4
      Chemical Name: 1,1',1''-phosphinothioylidynetris-aziridine
      Synonyms:Tiofosyl, Tiofosfamid, Triethylenethiophosphoramide
      分子量:189.22
      分子式:C₆H₁₂N₃PS
      SMILES:S=P(N1CC1)(N2CC2)N3CC3
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
      Select Batch:
      Purity: 98%
    • 产品描述: Thio-TEPA 是一种 DNA 烷化剂 (DNA alkylator),具有抗肿瘤作用。
      IC50和靶点:
      In Vitro:
      In Vivo:
      Clinical Trial:
      Solvent & Solubility:
    • Miller, B., Tenenholz, T., Egorin, M.J., et al.Cellular pharmacology of N,N',N''-triethylene thiophosphoramideCancer Lett.41(2),157-168(1988)

      Maanen, M.J., Smeets, C.J., and Beijnen, J.H.Chemistry, pharmacology and pharmacokinetics of N,N′,N′′-triethylenethiophosphoramide (ThioTEPA)Cancer Treat. Rev.26(4),257-268(2000)

      Kramer, W.M., and Schatten, W.E.An experimental study of triethylenethiophosphoramide (TSPA) in the prevention of postoperative pulmonary metastasesCancer11(3),463-465(1958)

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