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Rolitetracycline

Cat. No.:YN250782

  • CAS No. :751-97-3

    • 产品资料
    • 生物活性
    • 参考文献
    • 产品名称: Rolitetracycline
      CAS No.: 751-97-3
      Chemical Name: 4-(dimethylamino)-1,4S,4aS,5,5aS,6S,11,12aS-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-N-(1-pyrrolidinylmethyl)-2-naphthacenecarboxamide
      Synonyms:罗利环素/氢吡四环素
      分子量:527.57
      分子式:C₂₇H₃₃N₃O₈
      SMILES:O=C(C(C1=O)=C(O)[C@@H](N(C)C)[C@]2([H])C[C@]3([H])[C@](C)(O)C4=C(C(C3=C(O)[C@@]21O)=O)C(O)=CC=C4)NCN5CCCC5
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: Rolitetracycline,四环素衍生物,是一种广谱抗生素。Rolitetracycline 作为蛋白质合成抑制剂、抗原生动物药物和前药发挥作用。
      IC50和靶点:
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      In Vivo:
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      Solvent & Solubility:
    • Dashner, F.D.Combination of bacteriostatic and bactericidal drugs: lack of significant in vitro antagonism between penicillin, cephalothin, and rolitetracyclineAntimicrob. Agents Chemother.10(5),802-808(1976)

      Oradines, B., Rogier, C., Fusai, T., et al.In vitro activities of antibiotics against Plasmodium falciparum are inhibited by ironAntimicrob. Agents Chemother.45(6),1746-1750(2001)

      Howlett, D.R., George, A.R., Owen, D.E., et al.Common structural features determine the effectiveness of carvedilol, daunomycin and rolitetracycline as inhibitors of Alzheimer β-amyloid fibril formationBiochem J.343(Pt 2),419-423(1999)

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