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TBA-7371

Cat. No.:YN250816

  • CAS No. :1494675-86-3

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    • 生物活性
    • 参考文献
    • 产品名称: TBA-7371
      CAS No.: 1494675-86-3
      Chemical Name: N-(2-hydroxyethyl)-1-[(6-methoxy-5-methyl-4-pyrimidinyl)methyl]-6-methyl-1H-pyrrolo[3,2-b]pyridine-3-carboxamide
      Synonyms:AZ 7371,DprE1-IN-1
      分子量:355.39
      分子式:C₁₈H₂₁N₅O₃
      SMILES:O=C(C1=CN(CC2=NC=NC(OC)=C2C)C3=CC(C)=CN=C31)NCCO
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
      Select Batch:
      Purity: 98%
    • 产品描述: TBA-7371 是有效的,非共价的DprE1抑制剂。TBA-7371 具有强大的抗结核活性。
      IC50和靶点:
      In Vitro:
      In Vivo:
      Clinical Trial:
      Solvent & Solubility:
    • Chatterji, M., Shandil, R., Manjunatha, M.R., et al.1,4-azaindole, a potential drug candidate for treatment of tuberculosisAntimicrob. Agents Chemother.58(9),5325-5331(2014)

      Shirude, P.S., Shandil, R., Sadler, C., et al.Azaindoles: Noncovalent DprE1 inhibitors from scaffold morphing efforts, kill Mycobacterium tuberculosis and are efficacious in vivoJ. Med. Chem.56(23),9701-9708(2013)

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