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Moxifloxacin Hydrochloride

Cat. No.:YN250837

  • CAS No. :186826-86-8

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    • 产品名称: Moxifloxacin Hydrochloride
      CAS No.: 186826-86-8
      Chemical Name: 1-cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-7-[(4aS,7aS)-octahydro-6H-pyrrolo[3,4-b]pyridin-6-yl]-4-oxo-3-quinolinecarboxylic acid, monohydrochloride
      Synonyms:莫西沙星盐酸盐; BAY 12-8039
      分子量:437.89
      分子式:C₂₁H₂₅ClFN₃O₄
      SMILES:O=C(C1=CN(C2CC2)C3=C(C=C(F)C(N(C4)C[C@]5([H])[C@@]4([H])CCCN5)=C3OC)C1=O)O.Cl
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: Moxifloxacin Hydrochloride (BAY 12-8039) 是一种口服有效的 8-甲氧基喹诺酮类抗菌药物,用于急性细菌性鼻窦炎,慢性支气管炎的急性细菌性加重和感染性肺炎的研究。
      IC50和靶点:
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    • Woodcock, J.M., Andrews, J.M., Boswell, F.J., et al.In vitro activity of BAY 12-8039, a new fluoroquinoloneAntimicrob. Agents Chemother.41(1),101-106(1997)

      Goldstein, E.J., Citron, D.M., Hudspeth, M., et al.In vitro activity of Bay 12-8039, a new 8-methoxyquinolone, compared to the activities of 11 other oral antimicrobial agents against 390 aerobic and anaerobic bacteria isolated from human and animal bite wound skin and soft tissue infections in humansAntimicrob. Agents Chemother.41(7),1552-1557(1997)

      Schedletzky, H., Wiedemann, B., and Heisig, P.The effect of moxifloxacin on its target topoisomerases from Escherichia coli and Staphylococcus aureusJ. Antimicrob. Chemother.43(Suppl B),31-37(1999)

      Beisswenger, C., Honecker, A., Kamyschnikow, A., et al.Moxifloxacin modulates inflammation during murine pneumoniaRespir. Res.15:82,(2014)

      Miyazaki, E., Miyazaki, M., Chen, J.M., et al.Moxifloxacin (BAY12-8039), a new 8-methoxyquinolone, is active in a mouse model of tuberculosisAntimicrob. Agents Chemother.43(1),85-89(1999)

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