Mecillinam
Cat. No.：YN250890
| 产品名称: | Mecillinam |
| CAS No.: | 32887-01-7 |
| Chemical Name: | (2S,5R,6R)-6-[[(hexahydro-1H-azepin-1-yl)methylene]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid |
| Synonyms: | Amdinocillin; FL 1060 |
| 分子量: | 325.43 |
| 分子式: | C₁₅H₂₃N₃O₃S |
| SMILES: | O=C([C@@H](C(C)(C)S[C@]1([H])[C@@H]2/N=C/N3CCCCCC3)N1C2=O)O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Mecillinam (Amdinocillin) 是一种β 内酰胺类抗生素，具有广谱的抗革兰氏阴性菌的活性。 |
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Neu, H.C.Amdinocillin: A novel penicillin. Antibacterial activity, pharmacology and clinical usePharmacotherapy5(1),1-10(1985)
Fuchs, F., and Hamprecht, A.Results from a prospective in vitro study on the mecillinam (amdinocillin) susceptibility of EnterobacteralesAntimicrob. Agents Chemother63(4),e02402-02418(2019)
Sutaria, D.S., Moya, B., Green, K.B., et al.First penicillin-binding protein occupancy patterns of β-lactams and β-lactamase inhibitors in Klebsiella pneumoniaeAntimicrob. Agents Chemother.62(6),e00282-00218(2018)
Anderson, J.D., Eftekhar, F., Cleeland, R., et al.Comparative activity of mecillinam and ampicillin singly and in combination in the urinary bladder model and experimental mouse modelJ. Antimicrob. Chemother.8(2),121-131(1981)
