D-Cycloserine
Cat. No.：YN250900
| 产品名称: | D-Cycloserine |
| CAS No.: | 68-41-7 |
| Chemical Name: | 4R-amino-3-isoxazolidinone |
| Synonyms: | D-环丝氨酸 |
| 分子量: | 102.09 |
| 分子式: | C₃H₆N₂O₂ |
| SMILES: | O=C1[C@H](N)CON1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | D-Cycloserine 是一种靶向细菌细胞壁肽聚糖生物合成酶的抗生素。D-Cycloserine 是一种NMDA部分激动剂，可以改善认知功能。D-Cycloserine 还可用于耐多药结核病的研究。 |
| IC50和靶点: | |
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Hood, W.F., Compton, R.P., and Monahan, J.B.D-cycloserine: A ligand for the N-methyl-D-aspartate coupled glycine receptor has partial agonist characteristicsNeurosci. Lett.98(1),91-95(1989)
Flood, J.F., Morley, J.E., and Lanthorn, T.H.Effect on memory processing by D-cycloserine, an agonist of the NMDA/glycine receptorEur. J. Pharmacol.221(2-3),249-254(1992)
Feng, Z., and Barletta, R.G.Roles of Mycobacterium smegmatis D-alanine:D-alanine ligase and D-alanine racemase in the mechanisms of action of and resistance to the peptidoglycan inhibitor D-cycloserineAntimicrob. Agents Chemother.47(1),283-291(2003)
Caminero, J.A., Sotqiu, G., Zumla, A., et al.Best drug treatment for multidrug-resistant and extensively drug-resistant tuberculosisLancet Infect. Dis.10(9),621-629(2010)
