Olsalazine Disodium
Cat. No.：YN250931
| 产品名称: | Olsalazine Disodium |
| CAS No.: | 6054-98-4 |
| Chemical Name: | 3,3'-(1,2-diazenediyl)bis[6-hydroxy-benzoic acid, disodium salt |
| Synonyms: | 奥沙拉秦钠 |
| 分子量: | 346.20 |
| 分子式: | C₁₄H₈N₂Na₂O₆ |
| SMILES: | O=C(O[Na])C1=C(O)C=CC(/N=N/C2=CC(C(O[Na])=O)=C(O)C=C2)=C1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Olsalazine Disodium 是抗炎化合物，可作用于炎症性肠病和溃疡性结肠炎。 |
| IC50和靶点: | |
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Nugent, S.G., Kumar, D., Rampton, D.S., et al.Intestinal luminal pH in inflammatory bowel disease: Possible determinants and implications for therapy with aminosalicylates and other drugsGut48(4),571-577(2001)
Pamukcu, R., Hanauer, S.B., and Chang, E.B.Effect of disodium azodisalicylate on electrolyte transport in rabbit ileum and colon in vitro. Comparison with sulfasalazine and 5-aminosalicylic acidGastroenterology95(4),975-981(1988)
Mohsen, A.Q.M., Mulvey, D., Priddle, J.D., et al.Effects of olsalazine in the jejunum of the ratGut28(3),346-352(1987)
Murthy, S., Murthy, N.S., Coppola, D., et al.The efficacy of BAY y 1015 in dextran sulfate model of mouse colitisInflamm. Res.46(6),224-233(1997)
Niu, Y., Li, H., Gao, L., et al.Old drug, new indication: Olsalazine sodium reduced serum uric acid levels in mice via inhibiting xanthine oxidoreductase activityJ. Pharmacol. Sci.135(3),114-120(2017)
