Enoxacin hydrate
Cat. No.：YN250972
| 产品名称: | Enoxacin hydrate |
| CAS No.: | 84294-96-2 |
| Chemical Name: | 1,8-Naphthyridine-3-carboxylic acid, 1-ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-, hydrate (2:3) |
| Synonyms: | 依诺沙星倍半水合物; Enoxacin sesquihydrate; AT-2266 hydrate; CI-919 hydrate |
| 分子量: | 347.34 |
| 分子式: | C₁₅H₁₇FN₄O₃ . ₃/₂ H₂O |
| SMILES: | O=C(C1=CN(CC)C2=C(C=C(F)C(N3CCNCC3)=N2)C1=O)O.[1.5H2O] |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Enoxacin hydrate (Enoxacin sesquihydrate) 是一种氟喹诺酮，可以干扰 DNA 复制，抑制细菌 DNA 促旋酶 (IC50=126 µg/ml) 和拓扑异构酶 IV (IC50=26.5 µg/ml)。Enoxacin hydrate 有效抑制革兰氏阳性和阴性细菌。Enoxacin hydrate 是一种特异性的癌症生长抑制剂，可增强 TAR RNA 结合蛋白 2 (TRBP) 介导的 microRNA 加工。 |
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| Solvent & Solubility: |
Maeda, Tomoya. et al., J. Antibiot. Res. 72, 566-573(2019)
