Sulfamethoxazole
Cat. No.：YN250998
| 产品名称: | Sulfamethoxazole |
| CAS No.: | 723-46-6 |
| Chemical Name: | 4-amino-N-(5-methyl-3-isoxazolyl)-benzenesulfonamide |
| Synonyms: | 磺胺甲恶唑; Ro 4-2130 |
| 分子量: | 253.28 |
| 分子式: | C₁₀H₁₁N₃O₃S |
| SMILES: | O=S(C1=CC=C(N)C=C1)(NC2=NOC(C)=C2)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Sulfamethoxazole (Ro 4-2130) 是磺胺类抗菌素，用于细菌感染。Sulfonamides 是对氨基苯甲酸 (PABA) 的竞争性拮抗剂。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Hong, Y.-L., Hossler, P.A., Calhoun, D.H., et al.Inhibition of recombinant Pneumocystis carinii dihydropteroate synthetase by sulfa drugsAntimicrob. Agents Chemother.39(8),1756-1763(1995)
Greenwood, D., and O'Grady, F.Activity and interaction of trimethoprim and sulphamethoxazole against Escherichia coliJ. Clin. Pathol.29(2),162-166(1976)
Elwell, L.P., Wilson, H.R., Knick, V.B., et al.In vitro and in vivo efficacy of the combination trimethoprim-sulfamethoxazole against clinical isolates of methicillin-resistant Staphylococcus aureusAntimicrob. Agents Chemother.29(6),1092-1094(1986)
Schilling, J.D., Lorenz, R.G., and Hultgren, S.J.Effect of trimethoprim-sulfamethoxazole on recurrent bacteriuria and bacterial persistence in mice infected with uropathogenic Escherichia coliInfect. Immun.70(12),7042-7049(2002)
