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Sulfamethoxazole D4

Cat. No.:YN251000

  • CAS No. :1020719-86-1

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    • 参考文献
    • 产品名称: Sulfamethoxazole D4
      CAS No.: 1020719-86-1
      Chemical Name: 4-amino-N-(5-methyl-3-isoxazolyl)-benzene-2,3,5,6-d4-sulfonamide
      Synonyms:磺胺甲恶唑 D4; Ro 4-2130 D4
      分子量:257.30
      分子式:C₁₀H₇D₄N₃O₃S
      SMILES:O=S(C1=C([2H])C([2H])=C(N)C([2H])=C1[2H])(NC2=NOC(C)=C2)=O
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: Sulfamethoxazole D4 (Ro 4-2130 D4) 是一种 Sulfamethoxazole (Ro 4-2130) 氘代物。Sulfamethoxazole 是一种磺胺类抑菌抗生素。
      IC50和靶点:
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    • Hong, Y.-L., Hossler, P.A., Calhoun, D.H., et al.Inhibition of recombinant Pneumocystis carinii dihydropteroate synthetase by sulfa drugsAntimicrob. Agents Chemother.39(8),1756-1763(1995)

      Greenwood, D., and O'Grady, F.Activity and interaction of trimethoprim and sulphamethoxazole against Escherichia coliJ. Clin. Pathol.29(2),162-166(1976)

      Elwell, L.P., Wilson, H.R., Knick, V.B., et al.In vitro and in vivo efficacy of the combination trimethoprim-sulfamethoxazole against clinical isolates of methicillin-resistant Staphylococcus aureusAntimicrob. Agents Chemother.29(6),1092-1094(1986)

      Schilling, J.D., Lorenz, R.G., and Hultgren, S.J.Effect of trimethoprim-sulfamethoxazole on recurrent bacteriuria and bacterial persistence in mice infected with uropathogenic Escherichia coliInfect. Immun.70(12),7042-7049(2002)

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