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Isoniazid

Cat. No.:YN251002

  • CAS No. :54-85-3

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    • 生物活性
    • 参考文献
    • 产品名称: Isoniazid
      CAS No.: 54-85-3
      Chemical Name: 4-pyridinecarboxylic acid, hydrazide
      Synonyms:异烟肼; INH; Isonicotinic acid hydrazide; Isonicotinic hydrazide
      分子量:137.14
      分子式:C₆H₇N₃O
      SMILES:O=C(C1=CC=NC=C1)NN
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
      Select Batch:
      Purity: 98%
    • 产品描述: Isoniazid (INH) 是一种前药,必须被细菌过氧化氢酶 KatG 激活。Isoniazid 对快速分裂的分枝杆菌具有杀菌作用,并具有抗菌活性。
      IC50和靶点:
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      In Vivo:
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      Solvent & Solubility:
    • Wang, F., Langley, R., Gulten, R., et al.Mechanism of thioamide drug action against tuberculosis and leprosyJ. Exp. Med.204(1),72-78(2007)

      Phetsuksiri, B., Baulard, A.R., Cooper, A.M., et al.Antimycobacterial activities of isoxyl and new derivatives through the inhibition of mycolic acid synthesisAntimicrob. Agents Chemother.43(5),1042-1051(1999)

      Chang, K.C., Yew, W.W., Tam, C.M., et al.WHO group 5 drugs and difficult multidrug-resistant tuberculosis: A systematic review with cohort analysis and meta-analysisAntimicrob. Agents Chemother.57(9),4097-4104(2013)

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