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Levofloxacin

Cat. No.:YN251003

  • CAS No. :100986-85-4

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    • 参考文献
    • 产品名称: Levofloxacin
      CAS No.: 100986-85-4
      Chemical Name: (3S)-9-fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid
      Synonyms:左氧氟沙星; (-)-Ofloxacin
      分子量:361.37
      分子式:C₁₈H₂₀FN₃O₄
      SMILES:O=C(C(C1=O)=CN2[C@@H](C)COC3=C(N4CCN(C)CC4)C(F)=CC1=C23)O
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: Levofloxacin是合成的氟喹诺酮类抗生素,能抑制细菌DNA旋转酶的超螺旋活性,可阻止DNA复制。
      IC50和靶点:
      In Vitro:
      In Vivo:
      Clinical Trial:
      Solvent & Solubility:
    • Norrby, S.R.LevofloxacinExpert Opin. Pharmacother.1(1),109-119(1999)

      Mohammadhosseini, N., Alipanahi, Z., Alipour, E., et al.Synthesis and antibacterial activity of novel levofloxacin derivatives containing a substituted thienylethyl moiety.Daru.20(1),(2012)

      Takei, M., Fukuda, H., Kishii, R., et al.Target preference of 15 quinolones against Staphylococcus aureus, based on antibacterial activities and target inhibitionAntimicrob. Agents Chemother.45(12),3544-3547(2001)

      Entenza, J.M., Vouillamoz, J., Glauser, M.P., et al.Levofloxacin versus ciprofloxacin, flucloxacillin, or vancomycin for treatment of experimental endocarditis due to methicillin-susceptible or -resistant Staphylococcus aureusAntimicrob. Agents Chemother.41(8),1662-1667(1997)

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