Levofloxacin
Cat. No.:YN251003
产品名称: | Levofloxacin |
CAS No.: | 100986-85-4 |
Chemical Name: | (3S)-9-fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid |
Synonyms: | 左氧氟沙星; (-)-Ofloxacin |
分子量: | 361.37 |
分子式: | C₁₈H₂₀FN₃O₄ |
SMILES: | O=C(C(C1=O)=CN2[C@@H](C)COC3=C(N4CCN(C)CC4)C(F)=CC1=C23)O |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Levofloxacin是合成的氟喹诺酮类抗生素,能抑制细菌DNA旋转酶的超螺旋活性,可阻止DNA复制。 |
IC50和靶点: | |
In Vitro: | |
In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: |
Norrby, S.R.LevofloxacinExpert Opin. Pharmacother.1(1),109-119(1999)
Mohammadhosseini, N., Alipanahi, Z., Alipour, E., et al.Synthesis and antibacterial activity of novel levofloxacin derivatives containing a substituted thienylethyl moiety.Daru.20(1),(2012)
Takei, M., Fukuda, H., Kishii, R., et al.Target preference of 15 quinolones against Staphylococcus aureus, based on antibacterial activities and target inhibitionAntimicrob. Agents Chemother.45(12),3544-3547(2001)
Entenza, J.M., Vouillamoz, J., Glauser, M.P., et al.Levofloxacin versus ciprofloxacin, flucloxacillin, or vancomycin for treatment of experimental endocarditis due to methicillin-susceptible or -resistant Staphylococcus aureusAntimicrob. Agents Chemother.41(8),1662-1667(1997)