Dyclonine hydrochloride
Cat. No.：YN251022
| 产品名称: | Dyclonine hydrochloride |
| CAS No.: | 536-43-6 |
| Chemical Name: | 1-(4-butoxyphenyl)-3-(1-piperidinyl)-1-propanone, monohydrochloride |
| Synonyms: | 盐酸达克罗宁; Dyclocaine hydrochloride |
| 分子量: | 325.87 |
| 分子式: | C₁₈H₂₈ClNO₂ |
| SMILES: | O=C(C1=CC=C(OCCCC)C=C1)CCN2CCCCC2.Cl |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Dyclonine hydrochloride (Dyclocaine hydrochloride) 是润喉片的有效成分。Dyclonine hydrochloride 还具有显着的杀菌和杀真菌活性。 |
| IC50和靶点: | [{name:"ALDH2:35 μM (IC50)"},{name: "ALDH3:76 μM (IC50)"}] |
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Florestano, H.J., and Bahler, M.E.Antimicrobial properties of dyclonine hydrochloride, a new topical anestheticJ. Am. Pharm. Assoc.45(5),320-325(1956)
Okazaki, S., Shintani, S., Hirata, Y., et al.Synthetic lethality of the ALDH3A1 inhibitor dyclonine and xCT inhibitors in glutathione deficiency-resistant cancer cellsOncotarget9(73),33832-33843(2018)
Sahdeo, S., Scott, B.D., McMackin, M.Z., et al.Dyclonine rescues frataxin deficiency in animal models and buccal cells of patients with Friedreich's ataxiaHum. Mol. Genet.23(25),6848-6862(2014)
