Nalidixic acid
Cat. No.：YN251030
| 产品名称: | Nalidixic acid |
| CAS No.: | 389-08-2 |
| Chemical Name: | 1-ethyl-7-methyl-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid |
| Synonyms: | 萘啶酸 |
| 分子量: | 232.24 |
| 分子式: | C₁₂H₁₂N₂O₃ |
| SMILES: | O=C(C1=CN(CC)C2=C(C=CC(C)=N2)C1=O)O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Nalidixic acid，一种喹诺酮类抗生素 (antibiotic)，对革兰氏阳性和革兰氏阴性细菌均有效。Nalidixic acid 在较低浓度下以抑菌的方式起作用，而在较高浓度下具有杀菌作用。Nalidixic acid 抑制 DNA 促旋酶和拓扑异构酶 IV 的亚基，并可逆地阻止易感细菌中的 DNA 复制。 |
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Lesher, G.Y., Froelich, E.J., Gruett, M.D., et al.1,8-Naphthyridine derivatives. A new class of chemotherapeutic agentsJ. Med. Pharm. Chem.91,1063-1065(1962)
